We have an extensive collection of imino sugars from natural sources available on request. We can also offer semi-synthetic modifications of the natural products. Those listed on our website cover the most common natural products such as DNJ, DAB and DMDP, which are all broad spectrum and potent alpha-glucosidase inhibitors.
We also have calystegines which are specific beta-glucosidase and galactosidase inhibitors. Swainsonine is the best known of the alpha-mannosidase inhibitors and is a bicyclic indolizidine alkaloid, as is castanospermine, an alpha- and beta-glucosidase inhibitor.
The imino sugars can be very specific in their glucosidase inhibition, even, for example, amongst alpha-glucosidases. Their stability is high even in biological systems. Most appear to be readily bioavailable orally and are primarily excreted unchanged in urine.
|2,5-Dideoxy-2,5-imino-D-mannitol||IS0233||From £ 58.00 each||Product details|
|Kifunensine||IS0234||From £ 78.00 each||Product details|
|α-Homonojirimycin||IS0235||From £ 88.00 each||Product details|
|Deoxymannojirimycin hydrochloride||IS0237||From £ 43.00 each||Product details|
|1,4-Dideoxy-1,4-imino-D-mannitol hydrochloride||IS0238||Enquire for Price||Product details|
|6-Acetomido-6-deoxycastanospermine||IS0239||Enquire for Price||Product details|
|Deoxygalactonojirimycin||IS0241||Enquire for Price||Product details|
|Calystegine A3||IS0244||From £ 282.00 each||Product details|
|(2R,3R,4R,5R)-2-(3-hydroxy-4-methoxyphenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol||IS0250||Enquire for Price||Product details|
|(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(4-hydroxyphenyl)pyrrolidine-3,4-diol||IS0251||Enquire for Price||Product details|
|Swainsonine||IS0263||From £ 85.00 each||Product details|
|N-Methyl trans-4-hydroxy-L-proline||IS0298||From £ 80.00 each||Product details|
|N,N-Dimethyl cis-4-hydroxy-L-proline||IS0304||From £ 87.00 each||Product details|
|N-Methyl cis-4-hydroxymethyl-L-proline||IS0324||From £ 87.00 each||Product details|
|Castanospermine||IS0350||From £ 41.00 each||Product details|
|Calystegine B3||IS0401||From £ 282.00 each||Product details|
|7,7a-Diepialexine||IS0402||From £ 241.00 each||Product details|
|N,N-Dimethyl trans-4-hydroxy-L-proline||IS0446||Enquire for Price||Product details|
|6-epi-Castanospermine||IS0453||From £ 310.00 each||Product details|
|Australine HCl||IS0501||From £ 159.00 each||Product details|
|3,7a-Diepialexine||IS0602||Enquire for Price||Product details|